Targeted Drug Delivery

Targeted intrathecal drug delivery can be used to deliver analgesics in close proximity to their site of action—the spinal cord. This could be an approach for patients who develop tolerance or are refractory to systemic analgesics.5

If a patient’s severe chronic pain worsens, the patient may require alternative treatments. PRIALT is a non-narcotic treatment that uses targeted drug delivery.6

Important Safety Information

  • PRIALT should be administered intrathecally (IT) by or under the direction of a physician. PRIALT is not intended for intravenous (IV) administration.
  • The combination of PRIALT with intrathecal opiates has not been studied in placebo-controlled clinical trials and is not recommended.
  • PRIALT is for use only in the Medtronic SynchroMed® II Infusion System and the CADD-Micro Ambulatory Infusion Pump.
  • Advise patients to contact a physician if they experience new or worsening muscle pain, soreness, or weakness with or without darkened urine.

Please see full Prescribing Information, including BOXED Warning, and click here for additional Important Safety Information.

References: 5. Gerber HR. Intrathecal morphine for chronic benign pain. Best Pract Res Clin Anaesthesiol. 2003;17(3):429-442. 6. PRIALT [package insert]. Palo Alto, CA: Jazz Pharmaceuticals; February 2013.