Refractory to Oral Analgesics

  • Pain historypg6HCP_blue_man
    • 14 years severe chronic pain
    • Lumbar pain with bilateral lower extremity pain
    • Sedentary but capable of performing activities of daily living
  • Pain etiology and treatment history
    • Failed back surgery
    • Failed spinal cord stimulation
    • Takes oral opioids, antidepressant, anticonvulsant, sleeping aid, and stool softener
  • Assessment
    • Patient is getting limited pain relief and has become intolerant of treatment as systemic analgesics, including oral opioids, were escalated
    • IT pump was implanted
    • PRIALT introduced
  • Consider PRIALT as the first IT therapy option
    • PRIALT could be offered as an IT non-opioid alternative

Important Safety Information

Withdrawal From Opiates
PRIALT is not an opiate and cannot prevent or relieve the symptoms associated with the withdrawal of opiates. To avoid withdrawal syndrome when opiate withdrawal is necessary, do not abruptly reduce or withdraw opioid medications.

The most frequently reported adverse reactions (≥25%) in clinical trials (n=1254 PRIALT-treated patients) were dizziness, nausea, confusional state, and nystagmus. Slower titration of PRIALT may result in fewer serious adverse reactions and discontinuations for adverse reactions.
Please see full Prescribing Information, including BOXED Warning, and click here for additional Important Safety Information.

Refractory to Oral Analgesics
Refractory to IT Morphine