Actor portrayal.

What does PRIALT treat?

PRIALT is a prescription medicine used to treat severe chronic pain in adults who cannot take other treatments or when other treatments do not work, stop working, or cause bothersome side effects. PRIALT can only be delivered by or under the direction of a doctor who injects the medicine into your spinal fluid through a special device (a procedure called intrathecal infusion).

Discover
long-term,*
non-opioid pain relief

*PRIALT was studied in multiple open-label, long-term safety studies for up to 12 months.

What does PRIALT treat?

PRIALT is a prescription medicine used to treat severe chronic pain in adults who cannot take other treatments or when other treatments do not work, stop working, or cause bothersome side effects. PRIALT can only be delivered by or under the direction of a doctor who injects the medicine into your spinal fluid through a special device (a procedure called intrathecal infusion).

How your medication is delivered matters

Pain signals travel from the site of injury through nerve channels in the spine to reach the brain. With intrathecal therapy (IT), a pump is placed in the body with a catheter that delivers medication directly into the spinal fluid. The line can be placed close to where your specific injury or problem is located. IT therapy may help reduce the amount of oral medication you use to block pain because the medication enters the body right where pain signals travel.


avatar nerves graphic

You may be experiencing more than one type of pain

Your severe chronic pain condition may be a result of more than one cause – damage to body tissues (nociceptive), damage to the nervous system (neuropathic), or a mix of the two.

Diagram of human body with spine and brain highlighted. Pain is reduced; not all patients will have the same level of pain relief from PRIALT (pointing to brain). Pain signal interrupted (pointing to spine). Nerve channels; eg, N-type calcium channel –(pointing to lower back/spine). PRIALT enters spinal fluid channel (pointing to lower back/spine). Site of injury/pain (pointing to lower back/spine). Magnified section showing intrathecal pump

Pain that is partly neuropathic can show up in many different conditions†:

  • Diabetic neuropathy
  • HIV-related neuropathy
  • Complex regional pain syndrome
  • Multiple sclerosis
  • Lumbar radiculopathy
  • Failed back surgery syndrome
  • Cancer-related pain
  • Spinal cord injury
  • Phantom limb
  • Tumor compression
†This list does not cover all of the pain conditions that have neuropathic pain.

Neuropathic pain may not respond well to medications

PRIALT, like opioids, has been studied in many types of severe chronic pain, but may not be appropriate for all patients.

Is PRIALT right for you?

Ask your doctor about PRIALT

Icon of vial of PRIALT

Starting on PRIALT?

What you need to know about starting therapy

Icon of vial of PRIALT with 2 flags crossed over each other

Questions about treatment?

Contact a nurse who specializes in non-opioid intrathecal treatment for severe chronic pain

Icon of nurse's hat

Important Safety Information

What is the most important information I should know about PRIALT?

PRIALT may cause serious side effects including severe mental (psychiatric) problems and problems thinking.

Contact your healthcare provider immediately if you experience any of the following side effects while on PRIALT:

  • Confusion or feeling less alert
  • See or hear things that are not real (hallucinations)
  • Memory problems
  • Difficulty speaking
  • Changes in mood, new or worsening depression or suicidal thoughts
  • New muscle pain or muscle cramps

Who should NOT take PRIALT?

You should not take PRIALT if:

  • You have a mental health condition called psychosis, described as a loss of contact with reality, which may include delusions (believing things that are not actually true), or hallucinations (seeing or hearing things that are not real)
  • You are allergic to PRIALT or to any of its ingredients

What are the other possible serious side effects of PRIALT?

Mental (psychiatric) problems, difficulty thinking. PRIALT may cause psychiatric problems or make it difficult to think properly. People who are 65 years of age and older have a higher risk for confusion. PRIALT may cause or worsen depression, which increases the risk of suicide.

Reduced mental alertness. PRIALT can reduce your mental alertness or cause you to become unconscious. While taking PRIALT, avoid activities that require you to be alert and awake, and have full control of your body – examples of activities to avoid include operating machinery or driving a car.

Muscle problems. PRIALT can cause rare but serious muscle problems. Tell your doctor if you have any of the following:

  • New or worsening muscle pain, soreness, or weakness
  • Dark-colored urine

What should I tell my doctor before receiving treatment with PRIALT?

  • Before receiving PRIALT, tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines can increase the risk of experiencing confusion and reduced mental alertness with PRIALT.
  • Tell your doctor about all of your medical conditions, including if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.

What are the most common side effects of PRIALT?

  • Dizziness
  • Nausea
  • Confusion
  • Uncontrolled eye movements

These are not all the possible side effects of PRIALT. Your doctor may stop treatment if serious side effects happen. Be sure to contact your healthcare team right away if you have questions or are worried about any side effects.

What does PRIALT treat?

PRIALT is a prescription medicine used to treat severe chronic pain in adults who cannot take other treatments or when other treatments do not work, stop working, or cause bothersome side effects. PRIALT can only be delivered by or under the direction of a doctor who injects the medicine into your spinal fluid through a special device (a procedure called intrathecal infusion).

You are encouraged to report negative side effects of prescription drugs to the FDA at 1‑800‑FDA‑1088 or www.FDA.gov/medwatch. You may also contact ESTEVE Pharmaceuticals, S.A. at 1‑888‑306‑6259 or drugsafety.us@esteve.com.

Please see accompanying Full Prescribing Information, including BOXED WARNING.

Important Safety Information

What is the most important information I should know about PRIALT?

PRIALT may cause serious side effects including severe mental (psychiatric) problems and problems thinking.

Contact your healthcare provider immediately if you experience any of the following side effects while on PRIALT:

  • Confusion or feeling less alert
  • See or hear things that are not real (hallucinations)
  • Memory problems
  • Difficulty speaking
  • Changes in mood, new or worsening depression or suicidal thoughts
  • New muscle pain or muscle cramps

Who should NOT take PRIALT?

You should not take PRIALT if:

  • You have a mental health condition called psychosis, described as a loss of contact with reality, which may include delusions (believing things that are not actually true), or hallucinations (seeing or hearing things that are not real)
  • You are allergic to PRIALT or to any of its ingredients

What are the other possible serious side effects of PRIALT?

Mental (psychiatric) problems, difficulty thinking. PRIALT may cause psychiatric problems or make it difficult to think properly. People who are 65 years of age and older have a higher risk for confusion. PRIALT may cause or worsen depression, which increases the risk of suicide.

Reduced mental alertness. PRIALT can reduce your mental alertness or cause you to become unconscious. While taking PRIALT, avoid activities that require you to be alert and awake, and have full control of your body – examples of activities to avoid include operating machinery or driving a car.

Muscle problems. PRIALT can cause rare but serious muscle problems. Tell your doctor if you have any of the following:

  • New or worsening muscle pain, soreness, or weakness
  • Dark-colored urine

What should I tell my doctor before receiving treatment with PRIALT?

  • Before receiving PRIALT, tell your doctor about all of the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Certain medicines can increase the risk of experiencing confusion and reduced mental alertness with PRIALT.
  • Tell your doctor about all of your medical conditions, including if you are pregnant or plan to become pregnant, or are breastfeeding or plan to breastfeed.

What are the most common side effects of PRIALT?

  • Dizziness
  • Nausea
  • Confusion
  • Uncontrolled eye movements

These are not all the possible side effects of PRIALT. Your doctor may stop treatment if serious side effects happen. Be sure to contact your healthcare team right away if you have questions or are worried about any side effects.

What does PRIALT treat?

PRIALT is a prescription medicine used to treat severe chronic pain in adults who cannot take other treatments or when other treatments do not work, stop working, or cause bothersome side effects. PRIALT can only be delivered by or under the direction of a doctor who injects the medicine into your spinal fluid through a special device (a procedure called intrathecal infusion).

You are encouraged to report negative side effects of prescription drugs to the FDA at 1‑800‑FDA‑1088 or www.FDA.gov/medwatch. You may also contact ESTEVE Pharmaceuticals, S.A. at 1‑888‑306‑6259 or drugsafety.us@esteve.com.

Please see accompanying Full Prescribing Information, including BOXED WARNING.

Attention

If you click “Continue” below, you will leave the current site. ESTEVE is not responsible for the privacy policy of any third-party websites. We encourage you to read the privacy policy of every website you visit.

Continue
Cancel

Healthcare Professionals

The information contained in this section of the site is intended for US Healthcare Professionals only. Click Continue if you are a US Healthcare Professional.

Continue
Cancel

Healthcare Professionals

The information contained in this section of the site is intended for US Healthcare Professionals only. Click Continue if you are a US Healthcare Professional.

Continue
Cancel